semaglutide glp-1 analogue Literature Review] Structural Biophysics-Guided Computational Design of Semaglutide Analogues to Enhance GLP-1R Activation

semaglutide glp-1 analogue Literature Review] Structural Biophysics-Guided Computational Design of Semaglutide Analogues to Enhance GLP-1R Activation

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The Way of the Wind: Embracing Life While Walking the Camino do Santiago, by John W. Pearson, 2021, recounts one man’s experiences while walking the Camino de Santiago, a thirty-five day, five hundred mile walking journey from St. Jean Pied de Port in France to Santiago de Compostela in Spain. The journey follows a path tread by literally millions of pilgrims, or “pelegrinos”, as they seek to find something very person in the experience. The book is a travelogue recounting the miles of the daily trek, the people, stories, dining, lodging, and local services encountered along the way. There are a series of black and white photographs accenting the dialogue which give the reader a sense of involvement in the story. A nice touch was a simple map at the beginning to orient the reader along each day’s travel. I absolutely loved this book. It was enjoyable to read and I found myself slowing down near the end of the book to better savor the details. It warrants a double read to go back and let those early experiences soak in a bit more. I found the book to be educational, as I learned a lot about the historical significance of the route of the Camino, as well as specific landmarks along the way, such as a 10th century Roman bridge dwarfed by a new modern bridge overhead. I imagined myself walking along that ancient roadway, imagining what a pilgrim in 1300 must have thought. The dialogue is playful, recount with hours of walking, lively dinners, and crowded “albergues” (think camp dorm rooms with bunk beds). All was not rosy along the Camino. The narrative relates the aches of sore feet, legs, backs; the challenges of securing lodging and laundry; meanings lost in translation; inclement weather and treacherous roadways. Often mentioned are markers to honor the fallen dead along the Camino. About 2/3rds through the book, John recants his very personal reason for going on the pilgrimage, which he describes as “The Whale in the Room”, referring to the motivation of Captain Ahab in Moby Dick. His honesty and vulnerability bring the entire journey into focus. He brings the reader to the Cruz de Ferro, where pilgrims have stopped for millennium with their deepest meanings. I have known John Pearson since 1975, when we met in High School in El Paso, Texas. However, through the years, I moved and we lost close touch. There were many parts of this book of which I did not know the details. John’s story is very powerful, and will impact the reader deeply. Once you have read the book, you will have a clear idea of the experience, and can judge for yourself if the Camino de Santiago is calling you. For me, I found the book asking me not “WILL you go?”, but “WHEN will you go?”

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Reviewed in the United States on May 9, 2021

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Marcella

Lowell, US

★★★★★ 5

A remarkable story, illuminating and real.

Format: Paperback

This book is a journey, the author’s journey and potentially the reader’s as well. A story that at once reveals the author’s walk of hundreds of miles, intertwined through steps of ancient history, beautiful and interesting places, and traversed by countless people who through the ages embarked on similar journeys of their own. There is a revealing honesty that comes through these pages allowing the reader to feel vicariously on a kind of journey of one’s own. With great admiration for this writer and for all those who have traversed so consummate a pilgrimage, I found myself searching my own soul, visualizing the vast and beautiful detailed descriptions, enjoying the frequent humor and occasional hilarity, at times laughing out loud, feeling deeply moved, filled with questions and ideas about the ways we all find ourselves traveling our lives. The people, fellow pilgrims the writer meets along the way, the experiences they share on their subjective journeys, are honored by this author as are the lives of those who came before them over the centuries. It is a book filled with surprises, joy, pain, beauty. An absolutely awesome experience to read.

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Reviewed in the United States on July 8, 2021

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Moonchild

Massapequa, US

★★★★★ 4

Good book …but some comments….

Format: Paperback

I too, have to agree with another reviewer giving four stars. I also noticed his comments on beautiful women and wondered how “Leslie” at home felt about it as well. And the wine he mentions far outweighed any reference at all to the necessary need for water on such a walk. Comments in the last few chapters on walkers who only walked the last few miles seemed a bit snarky. But he made me laugh out loud several times and I found it to be an enjoyable, entertaining read. I can only hope Leslie, at home, felt the same ! Having read many books on the Camino, this was a good read. His tragic experience earlier in life makes me give him a hug and big thumbs up for finding meaning in life and going for it. Thanks, John.

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Reviewed in the United States on September 26, 2024

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Liz B.

Charlottesville, US

★★★★★ 5

How One Journey Can Change You Emotionally, Spiritually, and Personally!!!

Format: Paperback

i've been interested in the Camino de Santiago for several years. I have seen several Youtubes on the Camino, plus read other books. Nothing has stirred me as much as this book. I felt like I had walked the entire Camino with John. I was nervous when he was nervous, laughed when he laughed, and cried when he cried. He absolutely captures the entire Camino, right to the end. I learned so much, not only historically, but also emotionally and spiritually. When I got near the end of the book, I didn't want to finish it and put it down, because I didn't want the journey to end!!! But I'm glad that I picked it up the next day and finished it, because the best part was at the end. The emotions were overwhelming to me. Great book. Now, I just have to put on my shoes and go (but not without proper preparations!!!)

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Reviewed in the United States on May 13, 2021

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Joan

Fort Morgan, US

★★★★★ 5

The Best Narrative about the Real Camino

Format: Kindle

I have read many, many books about the Camino de Santiago and this is by far the best. It is so clearly written that I felt myself walking along with John Pearson. His description of every aspect of the Way is accurate and wonderful to read. I only walked the last 100 km, but feel now like I walked the whole way and enjoyed it without the blisters! If I were younger, I would definitely walk the entire way but am so glad John wrote his experience so that I at least can imagine what it was like. Thank you for the Most Excellent Book!

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Reviewed in the United States on June 1, 2021